Victor J. Hruby: search on Z-Library

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1

Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications

Vardanyan, Ruben S, Hruby, Victor J

Journal:

Future Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.91 MB

english, 2014

2

Sensitivity- and Gradient-Enhanced Heteronuclear Coupled/Decoupled HSQC–TOCSY Experiments for Measuring Long-Range Heteronuclear Coupling Constants

Katalin E. Kövér, Victor J. Hruby, Dušan Uhrı́n

Journal:

Journal of Magnetic Resonance

Year:

1997

Language:

english

File:

PDF, 122 KB

english, 1997

3

A new type of synthetic peptide library for identifying ligand-binding activity

Lam, Kit S., Salmon, Sydney E., Hersh, Evan M., Hruby, Victor J., Kazmierski, Wieslaw M., Knapp, Richard J.

Journal:

Year:

1991

File:

PDF, 477 KB

1991

4

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

Kesterson, Robert A., Hruby, Victor J., Cone, Roger D., Fan, Wei, Boston, Bruce A.

Journal:

Year:

1997

File:

PDF, 934 KB

1997

5

Design of Peptide and Peptidomimetic Ligands with Novel Pharmacological Activity Profiles

Hruby, Victor J., Cai, Minying

Journal:

Annual Review of Pharmacology

Year:

2013

Language:

english

File:

PDF, 789 KB

english, 2013

6

SYNTHETIC MELANOTROPIC PEPTIDE INITIATES ERECTIONS IN MEN WITH PSYCHOGENIC ERECTILE DYSFUNCTION: DOUBLE-BLIND, PLACEBO CONTROLLED CROSSOVER STUDY

WESSELLS, HUNTER, FUCIARELLI, KEVIN, HANSEN, JOHN, HADLEY, MAC E., HRUBY, VICTOR J., DORR, ROBERT, LEVINE, NORMAN

Journal:

The Journal of Urology

Year:

1998

Language:

english

File:

PDF, 616 KB

english, 1998

7

Solution structures of cyclic melanocortin agonists and antagonists by NMR

Jinfa Ying, Katalin E. Kövér, Xuyuan Gu, Guoxia Han, Dev B. Trivedi, Malcolm J. Kavarana, Victor J. Hruby

Journal:

Year:

2003

Language:

english

File:

PDF, 505 KB

english, 2003

8

Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity

Ravil R. Petrov, Ruben S. Vardanyan, Yeon S. Lee, Shou-wu Ma, Peg Davis, Lucinda J. Begay, Josephine Y. Lai, Frank Porreca, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 142 KB

english, 2006

9

The biological activity and metabolic stability of peptidic bifunctional compounds that are opioid receptor agonists and neurokinin-1 receptor antagonists with a cystine moiety

Takashi Yamamoto, Padma Nair, Shou-wu Ma, Peg Davis, Henry I. Yamamura, Todd W. Vanderah, Frank Porreca, Josephine Lai, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 298 KB

english, 2009

10

Squalene-derived flexible linkers for bioactive peptides

Bhumasamudram Jagadish, Rajesh Sankaranarayanan, Liping Xu, Reyniak Richards, Josef Vagner, Victor J. Hruby, Robert J. Gillies, Eugene A. Mash

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 171 KB

english, 2007

11

A new approach to enhance bioavailability of biologically active peptides: conjugation of a δ opioid agonist to β-cyclodextrin

Maria K. Hristova-Kazmierski, P. Horan, P. Davis, H.I. Yamamura, T. Kramer, R. Horvath, W.M. Kazmierski, F. Porreca, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 246 KB

english, 1993

12

The Melanotropic Peptide, [Nle4, d-Phe7]α-MSH, Stimulates Human Melanoma Tyrosinase Activity and Inhibits Cell Proliferation

JINWEN JIANG, SHUBH D. SHARMA, SHELLEY NAKAMURA, JENG-YU LAI, JODY L. FINK, VICTOR J. HRUBY, MAC E. HADLEY

Journal:

Pigment Cell & Melanoma Research

Year:

1995

Language:

english

File:

PDF, 1.08 MB

english, 1995

13

Melanocortin Receptors: Identification and Characterization by Melanotropic Peptide Agonists and Antagonists

MAC E. HADLEY, VICTOR J. HRUBY, JIWEN JIANG, SHUBH D. SHARMA, JODY L. FINK, CARRIE HASKELL-LUEVANO, DAVID L. BENTLEY, FAHAD AL-OBEIDI, TOMI K. SAWYER

Journal:

Pigment Cell & Melanoma Research

Year:

1996

Language:

english

File:

PDF, 2.51 MB

english, 1996

14

Cell Signaling and Trafficking of Human Melanocortin Receptors in Real Time Using Two-photon Fluorescence and Confocal Laser Microscopy: Differentiation of Agonists and Antagonists

Minying Cai, Eva V. Varga, Magda Stankova, Alexander Mayorov, Joseph W. Perry, Henry I. Yamamura, Dev Trivedi, Victor J. Hruby

Journal:

Chemical Biology & Drug Design

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

15

Agonist-specific down-regulation of the human δ-opioid receptor

Takashi Okura, Eva V. Varga, Yoshiaki Hosohata, Edita Navratilova, Scott M. Cowell, Kenner Rice, Hiroshi Nagase, Victor J. Hruby, William R. Roeske, Henry I. Yamamura

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 292 KB

english, 2003

16

cis -4-Amino- l -proline Residue As a Scaffold for the Synthesis of Cyclic and Linear Endomorphin-2 Analogues: Part 2

Mollica, Adriano, Pinnen, Francesco, Stefanucci, Azzurra, Mannina, Luisa, Sobolev, Anatoly P., Lucente, Gino, Davis, Peg, Lai, Josephine, Ma, Shou-Wu, Porreca, Frank, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 524 KB

english, 2012

17

Evaluation of Melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study

Robert T. Dorr, Ruskin Lines, Norman Levine, Christine Brooks, Li Xiang, Victor J. Hruby, Mac E. Hadley

Journal:

Year:

1996

Language:

english

File:

PDF, 596 KB

english, 1996

18

Techniques: Plasmon-waveguide resonance (PWR) spectroscopy as a tool to study ligand–GPCR interactions

Gordon Tollin, Zdzislaw Salamon, Victor J. Hruby

Journal:

Trends in Pharmacological Sciences

Year:

2003

Language:

english

File:

PDF, 413 KB

english, 2003

19

Synthesis of leucine enkephalin derivatives: Structure-function studies

Nirankar S. Agarwal, Victor J. Hruby, Robert Katz, Werner Klee, Marshall Nirenberg

Journal:

Biochemical and Biophysical Research Communications

Year:

1977

Language:

english

File:

PDF, 409 KB

english, 1977

20

VII. Topical application of a melanotropic peptide induces systemic follicular melanogenesis

Mac E. Hadley, Sterling H. Wood, Athena M. Lemus-Wilson, Brenda V. Dawson, Norman Levine, Robert T. Dorr, Victor J. Hruby

Journal:

Year:

1987

Language:

english

File:

PDF, 1.54 MB

english, 1987

21

Melanocyte stimulating hormone and melanin concentrating hormone may be structurally and evolutionarily related

Ana Maria de L. Castrucci, Mac E. Hadley, Michal Lebl, Christian Zechel, Victor J. Hruby

Journal:

Regulatory Peptides

Year:

1989

Language:

english

File:

PDF, 473 KB

english, 1989

22

Conformational restrictions of biologically active peptides via amino acid side chain groups

Victor J. Hruby

Journal:

Year:

1982

Language:

english

File:

PDF, 649 KB

english, 1982

23

Simple method for the synthesis of amides

Barstow, Leon E., Hruby, Victor J.

Journal:

Journal of Organic Chemistry

Year:

1971

Language:

english

File:

PDF, 294 KB

english, 1971

24

Asymmetric 1,4-addition of organocuprates to chiral .alpha.,.beta.-unsaturated N-acyl-4-phenyl-2-oxazolidinones: a new approach to the synthesis of chiral .beta.-branched carboxylic acids

Nicolas, Ernesto, Russell, K. C., Hruby, Victor J.

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 681 KB

english, 1993

25

Houben−Weyl Methods of Organic Chemistry. Volume E22A. Synthesis of Peptides and Peptidomimetics Edited by Murray Goodman, Arthur Felix, Luis Moroder, and Claudio Toniolo. Georg Thieme Verlag, Stuttgart, Germany. 2001. xxvii + 901 pp. 18 × 26 cm. ISBN 3 132 19604 5. 1840 euro.

Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 22 KB

english, 2002

26

Discovery of Prototype Peptidomimetic Agonists at the Human Melanocortin Receptors MC1R and MC4R

Haskell-Luevano, Carrie, Hendrata, Siska, North, Cheryl, Sawyer, Tomi K., Hadley, Mac E., Hruby, Victor J., Dickinson, Chris, Gantz, Ira

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 214 KB

english, 1997

27

A general method for the preparation of .alpha.-labeled amino acids

Upson, Donald A., Hruby, Victor J.

Journal:

Journal of Organic Chemistry

Year:

1977

Language:

english

File:

PDF, 308 KB

english, 1977

28

Synthesis of specifically deuterated S-benzylcysteines and of oxytocin and related diastereomers deuterated in the half-cystine positions

Upson, Donald A., Hruby, Victor J.

Journal:

Journal of Organic Chemistry

Year:

1976

Language:

english

File:

PDF, 920 KB

english, 1976

29

Structure−Activity Relationships of Bifunctional Peptides Based on Overlapping Pharmacophores at Opioid and Cholecystokinin Receptors

Agnes, Richard S., Lee, Yeon Sun, Davis, Peg, Ma, Shou-wu, Badghisi, Hamid, Porreca, Frank, Lai, Josephine, Hruby, Victor J.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

30

Biological and Conformational Examination of Stereochemical Modifications Using the Template Melanotropin Peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp- Ala-Lys]-NH 2 , on Human Melanocortin Receptors

Haskell-Luevano, Carrie, Nikiforovich, Gregory, Sharma, Shubh D., Yang, Ying-Kui, Dickinson, Chris, Hruby, Victor J., Gantz, Ira

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 332 KB

english, 1997

31

Hitting multiple targets with multimeric ligands

Handl, Heather L, Vagner, Josef, Han, Haiyong, Mash, Eugene, Hruby, Victor J, Gillies, Robert J

Journal:

Expert Opinion on Therapeutic Targets

Year:

2004

Language:

english

File:

PDF, 533 KB

english, 2004

32

Synthesis of oxytocin and related diastereomers deuterated in the half-cystine positions. Comparison of solid-phase and solution methods

Spatola, Arno F., Cornelius, Dennis A., Hruby, Victor J., Blomquist, Alfred T.

Journal:

Journal of Organic Chemistry

Year:

1974

Language:

english

File:

PDF, 866 KB

english, 1974

33

Conformational restriction of Tyr and Phe side chains in opioid peptides: Information about preferred and bioactive side-chain topology

Dirk Tourwé, Kris Verschueren, Anne Frycia, Peg Davis, Frank Porreca, Victor J. Hruby, Geza Toth, Hendrika Jaspers, Patricia Verheyden, Georges Van Binst

Journal:

Year:

1996

Language:

english

File:

PDF, 789 KB

english, 1996

34

Conformational analysis of β-methyl-para-nitrophenylalanine stereoisomers of cyclo[D-Pen2, D-Pen5]enkephalin by NMR spectroscopy and conformational energy calculations

Mark D. Shenderovich, Katalin E. Kövér, Gregory V. Nikiforovich, Ding Jiao, Victor J. Hruby

Journal:

Year:

1996

Language:

english

File:

PDF, 1.18 MB

english, 1996

35

Exploration of the conformational space of oxytocin and arginine-vasopressin using the electrostatically driven Monte Carlo and molecular dynamics methods

Adam Liwo, Anna Tempczyk, Stanislaw Oldziej, Mark D. Shenderovich, Victor J. Hruby, Sekhar Talluri, Jerzy Ciarkowski, Franciszek Kasprzykowski, Leszek Lankiewicz, Zbigniew Grzonka

Journal:

Year:

1996

Language:

english

File:

PDF, 1.42 MB

english, 1996

36

Editorial

Victor J. Hruby

Journal:

Year:

1997

Language:

english

File:

PDF, 11 KB

english, 1997

37

Design of peptides, proteins, and peptidomimetics in chi space

Victor J. Hruby, Guigen Li, Carrie Haskell-Luevano, Mark Shenderovich

Journal:

Year:

1997

Language:

english

File:

PDF, 1.29 MB

english, 1997

38

Conformation–activity relationships of opioid peptides with selective activities at opioid receptors

Victor J. Hruby, Richard S. Agnes

Journal:

Year:

1999

Language:

english

File:

PDF, 141 KB

english, 1999

39

Structure and dynamics of α-MSH using DRISM integral equation theory and stochastic dynamics

Ninad V. Prabhu, John S. Perkyns, B. Montgomery Pettitt, Victor J. Hruby

Journal:

Year:

1999

Language:

english

File:

PDF, 257 KB

english, 1999

40

A three-dimensional model of the δ-opioid pharmacophore: Comparative molecular modeling of peptide and nonpeptide ligands

Mark D. Shenderovich, Subo Liao, Xinhua Qian, Victor J. Hruby

Journal:

Year:

2000

Language:

english

File:

PDF, 359 KB

english, 2000

41

Skin Pigmentation and Pharmacokinetics of Melanotan-I in Humans

SYDNEY O. UGWU, JAMES BLANCHARD, ROBERT T. DORR, NORMAN LEVINE, CHRISTINE BROOKS, MAC E. HADLEY, MIKEL AICKIN, VICTOR J. HRUBY

Journal:

Biopharmaceutics & Drug Disposition

Year:

1997

Language:

english

File:

PDF, 152 KB

english, 1997

42

A Practical Asymmetric Synthesis of Enantiomerically Pure 3-Substituted Pyroglutamic Acids and Related Compounds

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby

Journal:

Angewandte Chemie

Year:

2000

Language:

english

File:

PDF, 103 KB

english, 2000

43

A Practical Asymmetric Synthesis of Enantiomerically Pure 3-Substituted Pyroglutamic Acids and Related Compounds

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

44

A Convenient, Room-Temperature–Organic Base Protocol for Preparing Chiral 3-(Enoyl)-1,3-oxazolidin-2-ones

Vadim A. Soloshonok, Hisanori Ueki, Changchun Jiang, Chaozhong Cai, Victor J. Hruby

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 89 KB

english, 2002

45

Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors: The Human Melanocortin-4 and δ-Opioid Receptors

Josef Vagner, Liping Xu, Heather L. Handl, Jatinder S. Josan, David L. Morse, Eugene A. Mash, Robert J. Gillies, Victor J. Hruby

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 423 KB

english, 2008

46

Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors: The Human Melanocortin-4 and δ-Opioid Receptors

Josef Vagner, Liping Xu, Heather L. Handl, Jatinder S. Josan, David L. Morse, Eugene A. Mash, Robert J. Gillies, Victor J. Hruby

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 423 KB

english, 2008

47

Structural characteristics of two highly selective opioid peptides

Richard J. Knapp, Henry I. Yamamura, Wieslaw Kazmierski, Victor J. Hruby

Journal:

Year:

1989

Language:

english

File:

PDF, 527 KB

english, 1989

48

Parallel synthesis and biological evaluation of different sizes of bicyclo[2,3]-Leu-enkephalin analogues

Xuyuan Gu, Jinfa Ying, Byoung Min, James P. Cain, Peg Davis, Patrick Willey, Edita Navratilova, Henry I. Yamamura, Frank Porreca, Victor J. Hruby

Journal:

Year:

2005

Language:

english

File:

PDF, 187 KB

english, 2005

49

Book review

Victor J. Hruby

Journal:

Year:

2007

Language:

english

File:

PDF, 52 KB

english, 2007

50

Conformational and dynamic considerations in the design of peptide hormone analogs

Victor J. Hruby, Henry I. Mosberg, Tomi K. Sawyer, James J. Knittel, Todd W. Rockway, James Ormberg, Paul Darman, W. Y. Chan, Mac E. Hadley

Journal:

Year:

1983

Language:

english

File:

PDF, 812 KB

english, 1983

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